Faculty Rank

Associate Professor

Undergraduate Education

Western Kentucky University, B.S. (Chemistry), 1976

Medical School

University of Louisville, Louisville, KY, M.D., 1980

Residency

University of Louisville, Louisville, KY (Pathology), 1980-1984

Fellowship

UMDNS-Robert Wood Johnson (Ortho Immunopathology Fellow), 1987

UNC-Chapel Hill, Chapel Hill, NC (NRSA, Oncologic Pathology), 1988-1991

Boards

American Board of Pathology, Clinical Pathology

American Board of Pathology, Anatomic Pathology

Clinical Interests

Transfusion Medicine

Research Interests

Monoclonal Antibodies to Tumor Associated Antigens (TAA) for Diagnostic Applications and Phenotyping of Human Tumors, Clinical Use of Monoclonal Antibodies to TAAs as Targeting Agents for Anticancer Therapy

Selected Publications

1.  Smith NL, Catrou PG, Payne G, Kellogg AE. Patterns of expression of the DS6-glycoform of MUC1 correlates with known prognostic indicators in breast cancer. Proceedings of the American Association of Cancer Research 2004; Vol 45. 

2.  Chun P, Xie H, Dionne CA, Medina LA, Lutz RJ, Seier TA, Kellogg AE, Payne G. Potent Anti-Cancer Activity of DS6-DM1, An Antibody-Drug Conjugate Targeting a MUC1 Glycotope on Ovarian, Breast and Pancreatic Carcinomas. Clin Cancer Res. 2003;9(16):6186s.

3.  Smith N, Halliday B, Finley J, Wennerberg A. The Spectrum of Immunohistochemical Reactivity of Monoclonal Antibody DS6 in Nongynecological Neoplasms. Applied Immunohistochemistry & Molecular Morphology. June 2002;10(2):152-158.

4.  Smith N, Halliday B, Finley J, Wennerberg A. Immunohistochemical Distribution of Tumor-associated Antigen CA6 in Gynecological Neoplasms as Detected by Monoclonal Antibody DS6. Int J Gyn Pathology. 2001;20:260-266.

5.  Kearse K, Smith N, Semer D, Eagles L, Finley J, Kazmierczak S, Kovacs C, Rodriguez A, Kellogg-Wennerberg A. Monoclonal Antibody DS6 Detects a Tumor-associated Sialoglycotope Expressed on Human Serous Ovarian Carcinomas. Int J Cancer. 2000;88:866-872. 

6.  Smith N, Semer D, Kerse K, Finley J, Wennerberg A. Immunohistochemically Detecting Target Antigens in Patient Biopsies for Tailoring Monoclonal Antibody Based Cancer Therapy. Human Antibodies. 1999;9:61-65.  

7.  Wennerberg A, Semer D, De Las Cases L, Kearse K. Target Antigens for Cancer Therapy: Correlation with Surgical Pathology Biopsies. Sixth International Conference on Human Antibodies and Hybridomas. 1998; Washington, DC.

8.  Demetris A, Seaberg E, Wennerberg A, Ionellie J, Michalopoulos G. The Ductular Reaction after Submassive Necrosis in Humans. American Journal of Pathology. 1966;149(2);439-448.

9.  Wennerberg A, Backman K, Gillerlain C, Robertson V, Jones C, Joyner T. Mixed Erythrocyte Chimerism: Implications for Tolerance of the Donor Immune System to Recipient non-ABO System Red Cell Antigens. Bone Marrow Transplantation. 1996; 18:433-435.

10. Wennerberg A, Nalesnik M and Coleman W. Hepatocyte Paraffin 1: A Monoclonal Antibody that Reacts with Hepatocytes and can be used for Differential Diagnosis of Hepatic Tumors. American Journal of Pathology. 1993;143(4):1050-1054.

11. Coleman W, Wennerberg A, Smith G, Grisham J. Regualtion of the Differentiation of Diploid and Some aneuploid Rate Liver Epithelial Stem Cells by the Hepatic Microenvironment. American Journal of Pathology. 1993;(5):1373-1381.

Selected Presentations

1.  Smith NL, Catrou PG, Payne G, Kellogg AE. Patterns of expression of the DS6-glycoform of MUC1 correlates with known prognostic indicators in breast cancer.  Poster presented at the 95th Annual Meeting of the AACR. Mar 27-31, 2004; Orlando, FL.

2.  Chun P, Kellogg AE, et al. Potent Anti-Cancer Activity of DS6-DM1, An Antibody-Drug Conjugate Targeting a MUC1 Glycotope on Ovarian, Breast, and Pancreatic Carcinomas. Poster presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. Nov 2003; Boston, MA.